The DOI displayed above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
DOI: 10.4121/81c9f2ce-25e2-4f62-bee5-a5cafa0d20c0

van den Berg, Daan Frits; Costa, Ana Rita; Brouns, Stan (2025): Data underlying the publication: Broad and specific anti-defense genes in bacteriophage genomes. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/81c9f2ce-25e2-4f62-bee5-a5cafa0d20c0.v1

Categories

• Microbiology
• Biological Sciences

Keywords

Bacteria Bacteriophage CRISPR-Cas Phage defense Pseudomonas

Licence

CC BY 4.0

Interoperability

• RO-Crate Metadata

Export as...

RefWorks BibTeX Reference Manager Endnote DataCite NLM DC CFF

by Daan Frits van den Berg , Ana Rita Costa , Stan Brouns

This dataset supports the study “Broad and specific anti-defense genes in bacteriophage genomes” and contains experimental and computational data used to investigate how phages overcome bacterial immune systems. The research objective was to identify and functionally characterize phage-encoded genes that either broadly inhibit multiple bacterial defense pathways or specifically target individual systems. Data were collected through comparative genomics of diverse phage genomes, systematic genetic screens, molecular cloning, and infection assays measuring bacterial survival and phage propagation. The dataset includes the phylogenetic tree of all analysed phages, the protein alignment and HMM profiles of the identified anti-genes and the corresponding code that was used.

History

• 2025-09-01 first online, published, posted

Publisher

4TU.ResearchData

Format

zip with *.xlsx, *.treefile, *.msa, *.hmm, *.ipynb, *.py, *.fasta

Associated peer-reviewed publication

Bacteriophage genomes encode both broad and specific counter-defense repertoires to overcome bacterial defense systems

Organizations

TU Delft, Kavli Institute of Nanoscience, Department of Bionanoscience, Brouns Lab