Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals.

doi: 10.4121/c.5065355.v2
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doi: 10.4121/c.5065355
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Eindhoven University of Technology; Department of Chemical Engineering and Chemistry Graz University of Technology; Institute of Process and Particle Engineering (IPPE) Delft University of Technology; Department of Biotechnology University of Bielefeld; France Faculty of Chemistry CNRS = National Center for Scientific Research (Centre National pour la Recherche Scientifique CNRS) et. al. (2021): Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals. Version 2. 4TU.ResearchData. collection. https://doi.org/10.4121/c.5065355.v2
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The ONE-FLOW project translates a ‘vertical hierarchy’ of chemical multistep synthesis with its complex machinery into a self-organising ‘horizontal hierarchy’ of a compartmentalized flow reactor system – a biomimetic digital flow cascade machinery with just one reactor passage. To keep the horizontal hierarchy manageable, orthogonality needs to be increased among the different consecutive reactions.
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  • 2021-12-30 first online, published, posted, revised
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4TU.Centre for Research Data