Eindhoven University of Technology; Department of Chemical Engineering and Chemistry Graz University of Technology; Institute of Process and Particle Engineering (IPPE) Delft University of Technology; Department of Biotechnology University of Bielefeld; France Faculty of Chemistry CNRS = National Center for Scientific Research (Centre National pour la Recherche Scientifique CNRS) et. al. (2019): Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals. Version 1. 4TU.ResearchData. collection. https://doi.org/10.4121/collection:ONE_Flow

Collection

x choose version: version 2 - 2021-12-30 (latest)

• Organic Chemistry
• Chemical Engineering

Biocatalysis, Catalyst Cascade Reactions, Chemical Process Engineering, Compartmentalization, Flow Cascades, Green Chemistry, Orthogonality, Synthetic Flow Reaction Networks

by Eindhoven University of Technology , Department of Chemical Engineering and Chemistry Graz University of Technology , Institute of Process and Particle Engineering (IPPE) Delft University of Technology , Department of Biotechnology University of Bielefeld , France Faculty of Chemistry CNRS = National Center for Scientific Research (Centre National pour la Recherche Scientifique CNRS) , LGPC unit University of Hull , Department of Chemistry and Biochemistry University of Cambridge , Graz Austria Department of Chemistry Microinnova Engineering GmbH

The ONE-FLOW project translates a ‘vertical hierarchy’ of chemical multistep synthesis with its complex machinery into a self-organising ‘horizontal hierarchy’ of a compartmentalized flow reactor system – a biomimetic digital flow cascade machinery with just one reactor passage. To keep the horizontal hierarchy manageable, orthogonality needs to be increased among the different consecutive reactions.

• 2021-12-30 first online

• 2019-04-10 published, posted

• 2020-07-17 revised

4TU.Centre for Research Data