Data underlying the publication: Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
dataset
posted on 2021-10-26, 11:30 authored by Louis KuijpersLouis Kuijpers, Nynke Dekker, Belen Solano HermosillaBelen Solano Hermosilla, Richard JanissenRichard JanissenThe research object was the characterization of two enterovirus RNA-dependent RNA polymerases using multiplexed magnetic tweezers, to investigate snap-back synthesis and recombination. Presented here are in vitro measurements of the bead position during RNA replication. Bead position measurements were taken for 2 hours a constant pulling force of 25 pN at 24C at a camera acquisition rate of 50 Hz. Traces were cropped from the start until the end of the change in z-position, which was converted to nucleotides.