Data underlying the publication: Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
doi: 10.4121/c.5608934.v1
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doi: 10.4121/c.5608934
doi: 10.4121/c.5608934
Datacite citation style:
Kuijpers, Louis; Dekker, Nynke H.; Belen Solano Hermosilla; Richard Janissen (2021): Data underlying the publication: Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses. Version 1. 4TU.ResearchData. collection. https://doi.org/10.4121/c.5608934.v1
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Collection
The research object
was the characterization of two enterovirus RNA-dependent RNA polymerases using
multiplexed magnetic tweezers, to investigate snap-back synthesis and
recombination. Presented here are in vitro measurements of the
bead position during RNA replication. Bead position measurements were taken for
2 hours a constant pulling force of 25 pN at 24C at a camera acquisition rate
of 50 Hz. Traces were cropped from the start until the end of the change in
z-position, which was converted to nucleotides.
history
- 2021-10-26 first online, published, posted, revised
publisher
4TU.ResearchData
associated peer-reviewed publication
Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
funding
- Human Frontiers Science Program (RPG0011/2015)
organizations
TU Delft, Faculty of Applied Sciences, Kavli Institute of Nanoscience, Department of Bionanoscience
