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Data from the research of Buyang Huanwu Decoction fraction attenuates oxidative stress damage via the SIRT1/FoxO1/PGC-1α route and the screening of neuroprotective components by cell membrane affinity chromatography.

dataset
posted on 09.06.2020 by xiangli yan
Buyang Huanwu decoction (BHD) is a famous prescription for treating ischemic stroke (IS), but its active ingredients remain unknown. To screen the neuroprotective ingredients from BHD fraction, we first investigated the protective effect of BHD fraction on middle cerebral artery occlusion (MCAO) rats, then screened the neuroprotective ingredients by membrane affinity chromatograph. The data we uploaded included neurological function scores, biochemical indicators, brain tissue sections, protein bands and some data on UPLC-QTOF/MS/MS.

Funding

National Natural Science Foundation of China, 81873228

Project of Educational Commission of Guangdong Province, 2017KZDXM018

Science Program for Overseas Scholar of Guangzhou University of Chinese Medicine, XH20170108

History

Contributors

Guangzhou University of Chinese Medicine, College of Traditional Chinese Medicine

Publisher

4TU.Centre for Research Data

Format

media types: application/vnd.ms-excel, application/vnd.openxmlformats-officedocument.spreadsheetml.sheet, application/zip, image/gif, text/plain

Licence

Exports