Data underlying the publication "Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress"

doi: 10.4121/12854801.v1
The doi above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
doi: 10.4121/12854801
Datacite citation style:
N. C. A (Nicole) van Engeland; Suarez Rodriguez, F. (Freddy); Adolfo Rivero-Müller; Tommaso Ristori; Camille L. Duran et. al. (2020): Data underlying the publication "Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress". Version 1. 4TU.ResearchData. dataset.
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The data and resulting publication combine in vivo animal studies on mice, cell biological in vitro experiments and computational modeling to study the role of the intermediate filament protein vimentin as a mechanosensitive regulator of Notch signaling and arterial remodeling. The dataset consists of computational simulation, fluorescence-assisted cell sorting, immunofluorescence and histological staining, luciferase reporter assay, quantitative real-time polymerase chain reaction and Western blotting data.
  • 2020-09-10 first online, published, posted
  • Targeting Notch signalign in cancer (grant code 218062) [more info...] Academy of Finland
  • The integration of cell signalling and mechanical forces in vascular morphology (grant code 771168) [more info...] European Research Council
  • Intelligent materials for in-situ heart Valve tissue engineering (grant code 604514) [more info...] European Commission
  • Doctoral Network of Molecular Biosciences at Åbo Akademi University
  • The Finnish Foundation for Cardiovascular Research
  • Maud Kuistila Memorial Foundation
  • The Swedish Cultural Foundation in Finland
  • Einar & Karin Stroems foundation
Åbo Akademi University, Faculty of Science and Engineering, Biosciences;
Eindhoven University of Technology, Department of Biomedical Engineering;
Åbo Akademi University and University of Turku, Turku Bioscience;
Medical University of Lublin, Department of Biochemistry and Molecular Biology;
Texas A&M University Health Science Center, Department of Molecular & Cellular Medicine;
University of Turku, Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology;
Eindhoven University of Technology, Institute of Complex Molecular Systems;
University of Turku, Turku Center for Disease Modelling


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