The doi above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
doi: 10.4121/17171069

Frans Bianchi; Peter Heeringa; Myrthe Frans; Anna van der Veen; Jildau van der Ven (2022): Data underlying the research of the Role of bacterial proteins in the onset of ANCA vasculitis. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/17171069.v1

Dataset

• Other Health

6pgd, AAV, ANCA, Anti-neutrophil cytoplasmic antibodies, MPO, Myeloperoxidase, SPIN, vasculitis

2021

CC BY 4.0

RefWorks, BibTeX, Reference Manager, Endnote, DataCite, NLM, DC, CFF

by Frans Bianchi , Peter Heeringa , Myrthe Frans , Anna van der Veen , Jildau van der Ven

Goal: The aim of the project was to investigate whether S.aureus proteins SPIN and 6PGD via the formation of the hybrid auto-antigen SPIN:MPO or MPO mimitope 6PGD could explain the differential aetiologies of the disease GPA (Granulomatosis with polyangitis) caused by MPO-ANCA (Anti Neutrophil Cytoplasmic Autoantibodies).Methods: Isolation kinetic verification of S.Aureus 6PGD and SPIN by means of Activity measurements, see Readme for further specifications. Determination of antibody reactivity/titers using ELISA in sera from patients with MPO ANCA and healthy individuals against the hybrid auto-antigen MPO:ANCA or 6PGD, see Readme for further specifications. Data: Antibody titers ELISA and (Kinetics) colorigenic activity assays.

• 2022-01-18 first online, published, posted

4TU.ResearchData

csv and txt

• ZONMW OffRoad (04510011910005)

University of Groningen, Faculty of Science and Engineering

E-mail name Reason

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