Data underlying the publication: Neuroprotective Effects of Everolimus via Regulation of Autophagy-Related Proteins in a Cerebral Ischemia-Reperfusion Rat Model

DOI:10.4121/983ad43d-4fad-4808-ade9-d30a03d836bb.v1
The DOI displayed above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
DOI: 10.4121/983ad43d-4fad-4808-ade9-d30a03d836bb

Datacite citation style

Fu, Shengling; Zhou, Yu-cong; Fang, Hu; Ouyang, Haoliang; Li, Shihua et. al. (2024): Data underlying the publication: Neuroprotective Effects of Everolimus via Regulation of Autophagy-Related Proteins in a Cerebral Ischemia-Reperfusion Rat Model. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/983ad43d-4fad-4808-ade9-d30a03d836bb.v1
Other citation styles (APA, Harvard, MLA, Vancouver, Chicago, IEEE) available at Datacite

Dataset

The data was collected from MCAO rats to evaluate the neuroprotection of everolimus. In excel file, the Longa’s neurological scale was applied to evaluate neurobehavioral deficit in ischemia/reperfusion-induced rats, and the ischemic infarct area of each section was calculated as infarct size. Besides, immunochemical staining of MCAO rats for mTOR and Beclin-1 expression was uploaded to observe the influence of everolimus on mTOR and Beclin-1. Besides, the data also included WB images of pPI3K, PI3K, pAkt, Akt, LC3-I, LC3-II. This study explored the effect of everolimus on the expression of PI3K, LC3, and Akt proteins and further clarified the regulatory mechanism of nerve cell autophagy against neural lesions.

History

  • 2024-08-01 first online, published, posted

Publisher

4TU.ResearchData

Format

*.xlsx, *.tif, *.png

Organizations

State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China

DATA

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