Research data supporting the PhD thesis Ovipositing the Prostate: Wasp-Inspired Needles for Prostate Laser Ablation

DOI:10.4121/43f41c07-65bb-42d5-bb60-e28a3d3f9954.v1
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DOI: 10.4121/43f41c07-65bb-42d5-bb60-e28a3d3f9954

Datacite citation style

Bloemberg, Jette (2025): Research data supporting the PhD thesis Ovipositing the Prostate: Wasp-Inspired Needles for Prostate Laser Ablation. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/43f41c07-65bb-42d5-bb60-e28a3d3f9954.v1
Other citation styles (APA, Harvard, MLA, Vancouver, Chicago, IEEE) available at Datacite

Dataset

Prostate cancer is one of the most common types of cancer in men, especially as they get older. Patients who are diagnosed with prostate cancer at an early stage can be eligible for TransPerineal Laser Ablation (TPLA). For MR-guided local treatments such as TPLA, control of the needle path is of utmost importance to accurately reach the target region. In order to reach the prostate, the needle is inserted transperineally. Commonly used needles are rigid and bound to straight trajectories, which might lead to restricted access because of pubic arch interference or targeting errors because of needle deflection caused by needle-tissue interaction. Therefore, using current needles makes it hard to control the needle trajectory and reach the target region. In nature, needle-like structures exist that allow for trajectory control. Specifically, certain species of parasitic wasps possess a slender and steerable needle-like structure called the ovipositor, of which they can control the trajectory. These wasps not only advance their ovipositors through often stiff substrates without suffering damage by using a so-called self-propelled motion, but they can also steer their ovipositors in order to reach their desired targets. Translating wasp-inspired mechanisms into novel needle designs might help to solve the current challenges with needles for TPLA applications. Therefore, the main purpose of this thesis is to present and evaluate innovative wasp-inspired needle designs developed to enhance needle trajectory control for TPLA treatment.

History

  • 2025-03-31 first online, published, posted

Publisher

4TU.ResearchData

Format

.docx, .pdf, .xlsx, .mp4, .ino, .m, .mov, .zip

Funding

  • Perspectief programme, Photonics Translational Research – Medical Photonics (MEDPHOT) (grant code 80450) [more info...] NWO-TTW

Organizations

TU Delft, Faculty of Mechanical Engineering, Department of BioMechanical Engineering

DATA

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