van Engeland, Suarez Rodriguez (2019) (252.62 MB)
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Data underlying the publication "Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress"

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posted on 10.09.2020, 15:24 authored by N. C. A (Nicole) van Engeland, F. (Freddy) Suarez Rodriguez, Adolfo Rivero-Müller, Tommaso Ristori, Camille L. Duran, O. M. J. A. (Oscar) Stassen, D. (Daniel) Antfolk, R.C.H. (Rob) Driessen, S. (Saku) Ruohonen, Suvi T. Ruohonen, S. (Salla) Nuutinen, Eriika Savontaus, S. (Sandra) Loerakker, Kayla J. Bayless, M. (Marika) Sjöqvist, C. V. C (Carlijn) Bouten, John E. Eriksson, C. M. (Cecilia) Sahlgren
The data and resulting publication combine in vivo animal studies on mice, cell biological in vitro experiments and computational modeling to study the role of the intermediate filament protein vimentin as a mechanosensitive regulator of Notch signaling and arterial remodeling. The dataset consists of computational simulation, fluorescence-assisted cell sorting, immunofluorescence and histological staining, luciferase reporter assay, quantitative real-time polymerase chain reaction and Western blotting data.


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The Finnish Foundation for Cardiovascular Research

Maud Kuistila Memorial Foundation

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Åbo Akademi University, Faculty of Science and Engineering, Biosciences; Eindhoven University of Technology, Department of Biomedical Engineering; Åbo Akademi University and University of Turku, Turku Bioscience; Medical University of Lublin, Department of Biochemistry and Molecular Biology; Texas A&M University Health Science Center, Department of Molecular & Cellular Medicine; University of Turku, Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology; Eindhoven University of Technology, Institute of Complex Molecular Systems; University of Turku, Turku Center for Disease Modelling