Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome (dataset)

Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome

doi:10.4121/18319907.v2

Datacite citation style:

Wang, Yan; Shen, Rui; Liu, Miao; Zhou, Qi; Zhai, Yan-hui et. al. (2022): Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome. Version 2. 4TU.ResearchData. dataset. https://doi.org/10.4121/18319907.v2

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Dataset

choose version: version 5 - 2022-08-24 (latest) version 4 - 2022-08-16 version 3 - 2022-02-24

version 2 - 2022-02-18

version 1 - 2022-01-14

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Pharmacology and Pharmaceutical Sciences

keywords

Intestinal Microbiota Composition, metagenomic sequencing, Tongxie Yaofang, Ulcerative colitis

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by Yan Wang , Rui Shen , Miao Liu , Qi Zhou , Yan-hui Zhai , Hui-Lin Fang , Yu-ze Lan , Zhu Xiang-dong

All rats were randomly divided into three groups: Control, Dinitrobenzene sulfonic acid (DNBS)-colitis, and DNBS+TXYF (n = 16). The physiological indexes of rats were detected. Compared with Control groups, a loss body weight, significant increased DAI score and CMDI score (P value < 0.01), as well as increased TNF-α level were observed in rats from the DNBS-colitis group, indicating that the UC model was successfully established. Meanwhile, TXYF treatment significantly decreased the DAI score, CMID score (P value < 0.01), and TNF-α level (P value < 0.05).

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