Wang, Yan; Shen, Rui; Liu, Miao; Zhou, Qi; Zhai, Yan-hui et. al. (2022): Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome. Version 2. 4TU.ResearchData. dataset. https://doi.org/10.4121/18319907.v2

Dataset

x choose version: version 5 - 2022-08-24 (latest) version 4 - 2022-08-16 version 3 - 2022-02-24 version 1 - 2022-01-14

• Pharmacology and Pharmaceutical Sciences

Intestinal Microbiota Composition, metagenomic sequencing, Tongxie Yaofang, Ulcerative colitis

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by Yan Wang , Rui Shen , Miao Liu , Qi Zhou , Yan-hui Zhai , Hui-Lin Fang , Yu-ze Lan , Zhu Xiang-dong

All rats were randomly divided into three groups: Control, Dinitrobenzene sulfonic acid (DNBS)-colitis, and DNBS+TXYF (n = 16). The physiological indexes of rats were detected. Compared with Control groups, a loss body weight, significant increased DAI score and CMDI score (P value < 0.01), as well as increased TNF-α level were observed in rats from the DNBS-colitis group, indicating that the UC model was successfully established. Meanwhile, TXYF treatment significantly decreased the DAI score, CMID score (P value < 0.01), and TNF-α level (P value < 0.05).

• 2022-01-14 first online

• 2022-02-18 published, posted

4TU.ResearchData

.xlsx .txt .tif

• National Natural Science Foundation of China (grant number 8167150826)

College of Basic Medicine, Gansu University of Chinese Medicine