The doi above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
doi: 10.4121/17055329

Marta Saccher; Kawasaki, Shinnosuke; Proietti Onori, Martina; van Woerden, Geeske M.; Giagka, Vasiliki et. al. (2021): Video recordings associated vith the pubblication: Focused ultrasound neuromodulation on MEA. Version 3. 4TU.ResearchData. dataset. https://doi.org/10.4121/17055329.v3

Dataset

x choose version: version 2 - 2021-11-23 version 1 - 2021-11-22

• Electrical and Electronic Engineering
• Biomedical Engineering

focused ultrasound, multielectrode arrays, neuromodulation, Ultrasound

CC0

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by Marta Saccher , Shinnosuke Kawasaki , Martina Proietti Onori , Geeske M. van Woerden , Vasiliki Giagka , Ronald Dekker

This dataset contains the video recording associated with the publication. In the first video, the multiwell MEA has been used to test the temperature variation during the period of US-ON. A thermocouple type K was placed at the bottom of the well and the ultrasound transducer immersed in the well. The input voltage was the same as the one used during the cell experiment and the MEA plate was placed on top of a hot plate to reproduce the experimental conditions. After 60 seconds of ultrasound the temperature increase was 0.8 °C.
In the second video, the heat profile generated by the ultrasound transducer used for the ultrasound neuromodulation experiment is observed using the Schlieren system. The trasnduecr is placed in the same Schlieren setup configuration used to validate the ultrasound field and a thermocouple is placed close to the tip of the transducer. The ultrasound is turned on for 60 seconds with a driving voltage 4.5 times higher than the one used during the cell experiment. It can be seen that the heat profile generated by the trasducer remains rather shallow the tip of the transducer and the water surface, suggesting that the heat does not reach the neuronal culture and it is dispersed at the liquid surface, rather than towards the neurons.

• 2021-11-22 first online

• 2021-11-25 published, posted

4TU.ResearchData

.mp4

• Accelerating Innovation in Microfabricated Medical Devices (grant code 876190) [more info...] European Commission
• Unravelling the function of CAMK2 in brain development and its role in neurodevelopmental disorders. (grant code 016.Vidi.188.014) [more info...] Dutch Research Council

TU Delft, Faculty of Electrical Engineering, Mathematics and Computer Science, Department of Microelectronics;
Department of Neuroscience, Erasmus MC, Rotterdam, the Netherlands; Department of Clinical Genetics, Erasmus MC, Rotterdam, the Netherlands