The doi above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
doi: 10.4121/1f95769f-e87e-4f38-8f15-b8865fc9e26d

Azizian Amiri, Sara; Dankelman, Jenny; Hendriks, Benno H. W. (2024): Data underlying the publication: Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery. Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/1f95769f-e87e-4f38-8f15-b8865fc9e26d.v1

Dataset

• Biomedical Engineering
• Engineering

breast phantom, Diffuse reflectance spectroscopy, DRS, electrosurgery phantom, optical phantom, tissue mimicking material

CC BY 4.0

RefWorks, BibTeX, Reference Manager, Endnote, DataCite, NLM, DC, CFF

by Sara Azizian Amiri , Jenny Dankelman , Benno H. W. Hendriks

Emerging intraoperative tumor margin assessment techniques require the development of more complex and reliable organ phantoms to assess the performance of the technique before its translation into the clinic. In this work, electrically conductive tissue-mimicking materials (TMMs) based on fat, water and agar/gelatin were produced with tunable optical properties. The composition of the phantoms allowed for the assessment of tumor margins using diffuse reflectance spectroscopy, as the fat/water ratio served as a discriminating factor between the healthy and malignant tissue. Moreover, the possibility of using polyvinyl alcohol (PVA) or transglutaminase in combination with fat, water and gelatin for developing TMMs was studied. The diffuse spectral response of the developed phantom materials had a good match with the spectral response of porcine muscle and adipose tissue, as well as in vitro human breast tissue. Using the developed recipe, anatomically relevant heterogeneous breast phantoms representing the optical properties of different layers of the human breast were fabricated using 3D-printed molds. These TMMs can be used for further development of phantoms applicable for simulating the realistic breast conserving surgery workflow in order to evaluate the intraoperative optical-based tumor margin assessment techniques during electrosurgery.

• 2024-12-10 first online, published, posted

4TU.ResearchData

Two spreadsheet/.xlsx-The absorption and scattering coefficients of different compositions at different wavelengths. One Comma-separated values/.CSV file-scattering coefficient of certain tissues and phantoms, one text file/.txt-Readme.

Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery

• Sensing in surgery (grant code 104006002) ZonMw

Faculty of Mechanical, Maritime, and Materials Engineering, Department of Biomechanical Engineering