The doi above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
doi: 10.4121/12854297

Tommaso Ristori; Stassen, O. M. J. A. (Oscar); Sahlgren, C. M. (Cecilia); Loerakker, S. (Sandra) (2020): Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls". Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/12854297.v1

Dataset

• Biomedical Engineering

agent-based model, artery, growth and remodeling, jagged, lateral induction, Notch signaling

2020

CC BY 4.0

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by Tommaso Ristori , O. M. J. A. (Oscar) Stassen , C. M. (Cecilia) Sahlgren , S. (Sandra) Loerakker

This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.

• 2020-10-20 first online, published, posted

4TU.ResearchData

Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls

• The integration of cell signalling and mechanical forces in vascular morphology (grant code 771168) [more info...] European Research Council
• Predicting cardiovascular regeneration: integrating mechanical cues and signaling pathways (grant code 802967) [more info...] European Research Council
• Targeting Notch signalign in cancer (grant code 218062) [more info...] Academy of Finland

Eindhoven University of Technology, Department of Biomedical Engineering;
Åbo Akademi University, Faculty of Science and Engineering, Biosciences;
Eindhoven University of Technology, Institute for Complex Molecular Systems