1. Introductory information 1.1 Title of the dataset Data underlying the publication: Does shear wave elastography for medullary thyroid carcinoma predict cervical lymph node metastasis? 1.2 Description of what data it contains Line 2-77: the included 76 patients with medullary thyroid carcinoma. Row A: the status of lateral cervical lymphatic metastasis, value "1" means positive and value "0" means negative. Row B: sex, value "0" means female and value "1" means male. Row C: age (years). Row D: age, value "1" means age ≤35 years and value "0" means age >35 years. Row E: size of mass (mm). Row F: size of mass, value "1" means size >10 mm and value "0" means size ≤10 mm. Row G: location of the mass, value "0" means central, value "1" means upper and value "2" means lower. Row H: pathologic ETE, value "1" means present and value "0" means absent. Row I: preoperative serum calcitonin (pg/ml) Row J: preoperative serum calcitonin, value "1" means calcitonin >60 pg/ml and value "0" means calcitonin ≤60 pg/ml. Row K: texture on US, value "1" means pure solid and value "0" means not pure solid. Row L: shape on US, value "1" means irregular and value "0" means regular. Row M: orientation on US, value "1" means parallel and value "0" means not parallel. Row N: margin on US, value "1" means not circumscribed and value "0" means circumscribed. Row O: calcification on US, value "0" means absent, value "1" means macrocalcification and value "2" means microcalcification. Row P: Emax (kPa) Row Q: Emax, value "1" means Emax >66 kPa and value "0" means Emax ≤66 kPa. Row R: Emean (kPa) Row S: Emean, value "1" means Emean >37.5 kPa and value "0" means Emean ≤37.5 kPa. Row T: ER Row U: ER, value "1" means ER >1.7 and value "0" means ER ≤1.7. 2. Methodological information 2.1 Method description for collecting and generating the data Consecutive patients with MTC who were treated with primary surgery at the Harbin Medical University Cancer Hospital between January 2014 and June 2019 were retrospectively reviewed. The data were collected by two authors and generated by another author. 2.2 Methods for processing data The continuous variables were shown as means ± standard deviations and the categorical variables were shown as number and percentage. The associations between the clinicopathological characteristics, the US features or SWE indices, and the cervical lymphatic types were evaluated by using independent t tests for the continuous variables and chi-square tests for the categorical variables. For the assessment of the independent clinicopathological and imaging predictors for lateral cervical LNM of MTC, a multivariable logistic regression analysis (forward: LR) was performed. All of the analyses in this study were performed with the use of SPSS version 22.0 (SPSS Inc., Chicago, IL, USA), with a P< 0.05 as the threshold for statistical significance. 3. Data specific information 3.1 Full names and definitions SWE: shear wave elastography. MTC: medullary thyroid carcinoma. LNM: lymph node metastasis. ETE: extrathyroidal extension. US: ultrasound. Emax: the maximum stiff value. Emean: the mean stiff value. ER: the ratio of Emean values between the mass and the parenchyma.