TY - DATA T1 - Transcriptomic analysis of human bronchial epithelium reveals unique immune landscape in severe asthma PY - 2022/04/13 AU - Qian Yan UR - https://data.4tu.nl/articles/dataset/Transcriptomic_analysis_of_human_bronchial_epithelium_reveals_unique_immune_landscape_in_severe_asthma/19537258/1 DO - 10.4121/19537258.v1 KW - Severe asthma KW - Weighted gene coexpression network analysis KW - ssGSEA KW - Immune infiltration KW - Gene set enrichment analysis (GSEA) KW - Single-sample GSEA (ssGSEA) N2 -

Airway epithelial transcriptome analysis of severe asthma (SA) patients was used to identify the immune infiltration mechanisms that affect asthma exacerbation, which may contribute to improving asthma therapy. A serises of bioinformatics methods were utilized to identify the hub genes and signaling pathways in SA. 

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