TY - DATA
T1 - Data underlying the publication: YAP/TAZ drives Notch and angiogenesis mechanoregulation in silico  
PY - 2024/10/08
AU - Margot Passier
AU - Katie Bentley
AU - Sandra Loerakker
AU - Tommaso Ristori
UR - 
DO - 10.4121/e12cc475-432a-4315-bc64-15a8888e3571.v1
KW - Computational model
KW - YAP/TAZ
KW - Notch
KW - mechanoregulation
KW - angiogenesis
KW - endothelial cells
N2 - <p>Data belonging to the article "YAP/TAZ drives Notch and angiogenesis mechanoregulation in silico"</p><p>It contains the MATLAB code used to run all simulations, the fitting algorithms and the code used to obtain all Figures.</p><p>The study focused on the mechanoresponse of Notch and in turn, that of angiogenesis. We hypothesized that this response could be explained through Notch interactions with mechano-sensitive YAP/TAZ. The modeled implementation was used to also investigate and suggest avenues through which to steer angiogenesis; by cytoskeletal manipulations and heterogeneous stiffness patterns.</p><p>DOI: <a href="https://doi.org/10.1038/s41540-024-00444-3" target="_blank"><u>https://doi.org/10.1038/s41540-024-00444-3</u></a></p>
ER -