TY - DATA
T1 - Data underlying the publication: Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
PY - 2021/10/26
AU - Louis Kuijpers
AU - Nynke Dekker
AU - Belen Solano Hermosilla
AU - Richard Janissen
UR - https://data.4tu.nl/articles/dataset/Data_underlying_the_publication_Induced_intra-_and_intermolecular_template_switching_as_a_therapeutic_mechanism_against_RNA_viruses/16866358/1
DO - 10.4121/16866358.v1
KW - Magnetic tweezer data
KW - magnetic tweezers
KW - virological characterizations
KW - RdRP activity
KW - RdRp pausing
N2 - <p>The research object  was the characterization of two enterovirus RNA-dependent RNA polymerases using multiplexed magnetic tweezers, to investigate snap-back synthesis and recombination. Presented here are <i>in vitro</i> measurements of the bead position during RNA replication. Bead position measurements were taken for 2 hours a constant pulling force of 25 pN at 24C at a camera acquisition rate of 50 Hz. Traces were cropped from the start until the end of the change in z-position, which was converted to nucleotides.</p><p><br></p><p><br></p>
ER -