TY - DATA T1 - Data and code underlying the publication: MUSICiAn: Genome-wide Identification of Genes Involved in DNA Repair via Control-Free Mutational Spectra Analysis PY - 2025/02/18 AU - Colm Seale AU - Marco Barazas AU - Robin van Schendel AU - Marcel Tijsterman AU - Joana Gonçalves UR - DO - 10.4121/b3f90f47-895b-4380-bf26-a79f76e9f47a.v1 KW - mutational spectra KW - control-free KW - outlier detection KW - compositional data analysis KW - DNA repair KW - DNA damage response KW - mahalanobis distance KW - CRISPR KW - isometric log-ratio transformation N2 -

This repository consists of code to reproduce the results of the paper "MUSICiAn: Genome-wide Identification of Genes Involved in DNA Repair via Control-Free Mutational Spectra Analysis".


The code to reproduce the paper is shared at: https://github.com/joanagoncalveslab/MUSICiAn


No experimental data was collected as part of this project, this project only utilised previously publicly available datasets. Details on accessing this data are fully described in the Methods section; "Data and preprocessing", "Mutational outcome data".



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