TY - DATA T1 - Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome PY - 2022/02/24 AU - Yan Wang AU - Rui Shen AU - Miao Liu AU - Qi Zhou AU - Yan-hui Zhai AU - Hui-Lin Fang AU - Yu-ze Lan AU - Zhu Xiang-dong UR - https://data.4tu.nl/articles/dataset/Raw_data_of_Metagenomic_analysis_of_Tongxie_Yaofang_in_treating_rat_model_of_ulcerative_colitis_with_the_liver_depression_and_spleen_deficiency_syndrome/18319907/3 DO - 10.4121/18319907.v3 KW - Ulcerative colitis KW - Tongxie Yaofang KW - metagenomic sequencing KW - Intestinal Microbiota Composition N2 - All rats were randomly divided into three groups: Control, Dinitrobenzene sulfonic acid (DNBS)-colitis, and DNBS+TXYF (n = 16). The physiological indexes of rats were detected. Compared with Control groups, a loss body weight, significant increased DAI score and CMDI score (P value < 0.01), as well as increased TNF-α level were observed in rats from the DNBS-colitis group, indicating that the UC model was successfully established. Meanwhile, TXYF treatment significantly decreased the DAI score, CMID score (P value < 0.01), and TNF-α level (P value < 0.05). ER -