TY - DATA
T1 - Data underlying the publication:  Dynamic compartment models: Towards a rapid modeling approach for fed-batch fermentations
PY - 2024/12/11
AU - Héctor Maldonado de León
AU - Adrie Straathof
AU - Cees Haringa
UR - 
DO - 10.4121/0a08d2ec-8959-403f-afea-2b085dc9f3a6.v1
KW - Computational fluid dynamics
KW - bioprocess
KW - industrial fermentation
KW - Compartment modelling
KW - CFD
KW - fermentation
N2 - <p>This data includes the files for developing a workflow to simulate fed-batch fermentations using a hybrid modeling approach based on flow-informed compartment models (CFD-CM) and a machine learning (ML) method. The proposed workflow circumvents the need for re-calibration of the compartment model upon changes in the working volume and stirring rate of the system. This is done using an inferring module based on a neural network. The methods to deploy the framework are described in the publication 'Dynamic compartment models: Towards a rapid modeling approach for fed-batch fermentations'. The dataset includes the case and data files from FLUENT to generate the parameterization of the compartment models (i.e., intercompartmental fluxes - .csv files) used for training and testing of the neural network, which is also included. These files aim to ensure the reproducibility of the results presented in the corresponding publication.</p>
ER -