%0 Computer Program %A Barth, Roman %D 2024 %T Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion" %U %R 10.4121/f60f272e-c66a-4755-942d-6de6f62a10ed.v1 %K Cohesin %K DNA supercoiling %K DNA loop extrusion %K Monte Carlo simulation %K plasmid assay %X
Research objective: computationally determine the linking number of plasmids after SMC-mediated DNA loop extrusion with twist and topoisomerase-mediated Lk change
Type of research: Comparison of computational model to experimental bulk plasmid assays
Method of data collection: 1D Monte Carlo simulations
Type of data: custom python code (.py) and .json data file
%I 4TU.ResearchData