%0 Generic %A van Asten, Jordy %A Ristori, Tommaso %A Nolan, David %A Lally, CaitrĂ­ona %A Baaijens, Frank %A Sahlgren, Cecilia %A Loerakker, Sandra %D 2022 %T Data belonging to the publication: "Computational analysis of the role of mechanosensitive Notch signaling in arterial adaptation to hypertension" %U https://data.4tu.nl/articles/dataset/Data_belonging_to_the_publication_Computational_analysis_of_the_role_of_mechanosensitive_Notch_signaling_in_arterial_adaptation_to_hypertension_/20237562/1 %R 10.4121/20237562.v1 %K Finite Element model %K Agent-Based model %K Hypertension %K Notch signaling %K Growth and remodeling %K Mechanobiology %X

This study couples a Finite Element model for arterial mechanics to an Agent-Based model for mechanosensitive Notch signaling among vascular smooth muscle cells to predict the phenotype of these cells under hypertension, a loss of residual stresses in the artery, and manipulations of the Notch signaling pathway. This dataset contains the codes for the Finite Element model, the Agent-Based model and the coupling between them, as well as the raw data generated by these models.

%I 4TU.ResearchData