%0 Generic
%A Kuijpers, Louis
%A Dekker, Nynke
%A Solano Hermosilla, Belen
%A Janissen, Richard
%D 2021
%T Data underlying the publication: Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
%U https://data.4tu.nl/articles/dataset/Data_underlying_the_publication_Induced_intra-_and_intermolecular_template_switching_as_a_therapeutic_mechanism_against_RNA_viruses/16866358/1
%R 10.4121/16866358.v1
%K Magnetic tweezer data
%K magnetic tweezers
%K virological characterizations
%K RdRP activity
%K RdRp pausing
%X <p>The research object  was the characterization of two enterovirus RNA-dependent RNA polymerases using multiplexed magnetic tweezers, to investigate snap-back synthesis and recombination. Presented here are <i>in vitro</i> measurements of the bead position during RNA replication. Bead position measurements were taken for 2 hours a constant pulling force of 25 pN at 24C at a camera acquisition rate of 50 Hz. Traces were cropped from the start until the end of the change in z-position, which was converted to nucleotides.</p><p><br></p><p><br></p>
%I 4TU.ResearchData