%0 Computer Program
%A Seale, Colm
%A Barazas, Marco
%A van Schendel, Robin
%A Tijsterman, Marcel
%A Gonçalves, Joana
%D 2025
%T Data and code underlying the publication: MUSICiAn: Genome-wide Identification of Genes Involved in DNA Repair via Control-Free Mutational Spectra Analysis
%U 
%R 10.4121/b3f90f47-895b-4380-bf26-a79f76e9f47a.v1
%K mutational spectra
%K control-free
%K outlier detection
%K compositional data analysis
%K DNA repair
%K DNA damage response
%K mahalanobis distance
%K CRISPR
%K isometric log-ratio transformation
%X <p>This repository consists of code to reproduce the results of the paper "MUSICiAn: Genome-wide Identification of Genes Involved in DNA Repair via Control-Free Mutational Spectra Analysis".</p><p><br></p><p>The code to reproduce the paper is shared at: <a href="https://github.com/joanagoncalveslab/MUSICiAn" target="_blank">https://github.com/joanagoncalveslab/MUSICiAn</a></p><p><br></p><p>No experimental data was collected as part of this project, this project only utilised previously publicly available datasets. Details on accessing this data are fully described in the Methods section; "Data and preprocessing", "Mutational outcome data".</p><p><br></p><p><br></p>
%I 4TU.ResearchData