%0 Generic %A Wang, Yan %A Shen, Rui %A Liu, Miao %A Zhou, Qi %A Zhai, Yan-hui %A Fang, Hui-Lin %A Lan, Yu-ze %A Xiang-dong, Zhu %D 2022 %T Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome %U https://data.4tu.nl/articles/dataset/Raw_data_of_Metagenomic_analysis_of_Tongxie_Yaofang_in_treating_rat_model_of_ulcerative_colitis_with_the_liver_depression_and_spleen_deficiency_syndrome/18319907/5 %R 10.4121/18319907.v5 %K Ulcerative colitis %K Tongxie Yaofang %K metagenomic sequencing %K Intestinal Microbiota Composition %X

All rats were randomly divided into three groups: Control, Dinitrobenzene sulfonic acid (DNBS)-colitis, and DNBS+TXYF (n = 8). The physiological indexes of rats were detected. Compared with Control groups, a loss body weight, significant increased DAI score and CMDI score (P value < 0.01) were observed in rats from the DNBS-colitis group, indicating that the UC model was successfully established. Meanwhile, TXYF treatment significantly decreased the DAI score, CMID score, and TNF-α level (P value < 0.05).  

%I 4TU.ResearchData