%0 Generic
%A Tang, Haibo
%A Li, Xiaoning
%A Cai, Jianhong
%A wu, xiaomin
%D 2022
%T Data for the paper: ‘Effects of different factors on the efficacy of anti PD-(L)1 monotherapy in patients with advanced non-small cell lung cancer: An observational, retrospective cohort study’
%U https://data.4tu.nl/articles/dataset/Data_for_the_paper_Effects_of_different_factors_on_the_efficacy_of_anti_PD-_L_1_monotherapy_in_patients_with_advanced_non-small_cell_lung_cancer_An_observational_retrospective_cohort_study_/19606378/1
%R 10.4121/19606378.v1
%K Lung Cancer
%K epidermal growth factor receptor (EGFR)
%K immunotherapy
%X <p>Effects of sex, age, EGFR mutation status and smoking status on immunotherapy.  we showed that the benefits for PFS and OS were similar in male and female, and in younger (< 65 years of age) and older (≥65 years of age) patients. EGFR mutation status and smoking status are two independent influencing factors. Regardless of EGFR mutation status, the ORR and PFS of current-smokers were better than those of never-smokers; The benefits of immunotherapy for other mutant subtypes except 19del, L858R and T790M were similar to those of EGFR wild-type; Former-smokers are a unique population who benefit poor from immunotherapy than never-smokers or current-smokers. </p>
%I 4TU.ResearchData