cff-version: 1.2.0 abstract: "
The data was collected from MCAO rats to evaluate the neuroprotection of everolimus. In excel file, the Longa’s neurological scale was applied to evaluate neurobehavioral deficit in ischemia/reperfusion-induced rats, and the ischemic infarct area of each section was calculated as infarct size. Besides, immunochemical staining of MCAO rats for mTOR and Beclin-1 expression was uploaded to observe the influence of everolimus on mTOR and Beclin-1. Besides, the data also included WB images of pPI3K, PI3K, pAkt, Akt, LC3-I, LC3-II. This study explored the effect of everolimus on the expression of PI3K, LC3, and Akt proteins and further clarified the regulatory mechanism of nerve cell autophagy against neural lesions.
" authors: - family-names: Fu given-names: Shengling - family-names: Zhou given-names: Yu-cong - family-names: Fang given-names: Hu - family-names: Ouyang given-names: Haoliang - family-names: Li given-names: Shihua - family-names: Xiao given-names: Jinping - family-names: Liu given-names: Hao title: "Data underlying the publication: Neuroprotective Effects of Everolimus via Regulation of Autophagy-Related Proteins in a Cerebral Ischemia-Reperfusion Rat Model" keywords: version: 1 identifiers: - type: doi value: 10.4121/983ad43d-4fad-4808-ade9-d30a03d836bb.v1 license: CC BY-NC-SA 4.0 date-released: 2024-08-01