cff-version: 1.2.0
abstract: "This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared."
authors:
  - family-names: Ristori
    given-names: Tommaso
    orcid: "https://orcid.org/0000-0002-2800-0067"
  - family-names: Stassen
    given-names: O. M. J. A. (Oscar)
    orcid: "https://orcid.org/0000-0001-7485-0903"
  - family-names: Sahlgren
    given-names: C. M. (Cecilia)
    orcid: "https://orcid.org/0000-0003-3350-4937"
  - family-names: Loerakker
    given-names: S. (Sandra)
    orcid: "https://orcid.org/0000-0002-9574-1623"
title: "Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls""
keywords:
version: 1
identifiers:
  - type: doi
    value: 10.4121/12854297.v1
license: CC BY 4.0
date-released: 2020-10-20